International Journal of Physiology
  • Year: 2019
  • Volume: 7
  • Issue: 4

Evaluation of Absolute Eosinophil Count and Peak Expiratory Flow Rate in COPD Patients

1Professor & HOD, Department of Pathology, Santhiram Medical College, Nandyal, Kurnool District, Andhra Pradesh, India

2Designed Associate Professor, Department of Physiology, Kurnool Medical College, Kurnool, Andhra Pradesh, India

3Post Graduate Student, Department of Pathology, Santhiram Medical College, Nandyal

*Corresponding Author: Dr. Payasam Rajeswari Designed Associate Professor, Department of Physiology, Kurnool Medical College, Kurnool, AP, India

Online published on 21 November, 2019.

Abstract

Chronic obstructive pulmonary disease (COPD) is a major public health problem leading to high health care utilizations, poor health-related quality of life, and substantial cost burden and deaths worldwide.

To assess the peak expiratory flow rate (PEFR) and absolute eosinophil count (AEC) in COPD patients.

This observational study was carried out among 80 COPD patients, volunteers referred from Medicine department of Santhiram Medical College. PEFR recorded was correlated with eosinophils.

The mean PEFR value was 214.7 ± 49.39 and mean absolute eosinophil count value was 749.7 ± 152.01. There was strong negative significant correlation (−0.80) between PEFR and absolute eosinophil count (p < 0.05).

The findings indicated that whenever the blood parameter eosinophils increased, there was a decrease in the PEFR in COPD patients.

Keywords

COPD, Peak expiratory flow rate, absolute eosinophil count