Department of Pharmaceutical Chemistry, St. Joseph's College of Pharmacy, Cherthala-688524, India
Online published on 13 May, 2015.
Various N-[3-Chloro-2-(substituted)-4-oxazetidin-1-yl]-4-(1H-indol-3-yl) butanamide derivatives have been synthesized by the cyclo condensation of Schiff bases with tri ethyl amine and chloro acetyl chloride. The structures of the newly synthesized compounds have been established on the basis of their spectral data. All compounds were evaluated for a-amylase inhibitory activity. All compounds investigated exhibited significant activity, comparable to that of the standard used.
N-[3-Chloro-2-(4-hydroxy-3-methoxy phenyl)-4-oxazetidin-1-yl]-4-(1H-indol-3-yl) butanamide, a-amylase inhibitor
