1Dept of Pharmaceutical Chemistry, Hamdard University, New Delhi-110062, India
2Health Information Technology Department, Jeddah Community College, King Abdulaziz University, Jeddah-21589, KSA
3Dept of Pharmacy, Oman Medical College, PO Box 620, Muscat, Oman
*Corresponding author: E-mail: myzoon@rediffmail.com, mymoonaakhter@gmail.com
Online published on 28 July, 2016.
The aim of this study was to evaluate the in vitro anthelmintic activity of 2-Arylidene-4-(substituted aryl)but-3-en-4olides (I-IX) against Indian earthworm i.e. Pheretima posthuma. The anthelmintic activity of nine butenolide derivatives was determined by recording the mean paralyzing and death times of the worms at concentration of 2 mg/mL. The results indicated that few of the tested butenolide derivatives possess significant anthelmintic activity comparable to positive control, albendazole.
Furanone, Pheretima posthuma, Anthelmintic, Albendazole
