Dept. of Pharmaceutical Analysis, Care College of Pharmacy, Warangal, Telangana
*Corresponding Author: Email: kumaraswamy.gandla@gmail.com
Online published on 19 September, 2016.
A simple, precise, rapid and reproducible stability indicating RP-HPLC method was developed and validated for the determination of Rufinamide in pharmaceutical dosage forms. Chromatography was performed on a C18 (ODS) Acetonitrile: water: Triethylamine buffer pH4.6: Methanol (70: 20: 10 v/v) was used as mobile phase and flow rate was adjusted to 0.8 ml/min. The detection was carried out at 292 nm using analytical Tech. UV-Visible detector SpD-10AVP. The obtained calibration curve was linear in the concentration range of 10-50ug/ml. The limit of detection and quantification was found to be 1.056 ug/ml and
Rufinamide, Reverse phase-HPLC, PDA, and Tablet dosage forms
