Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 1

The Role of CYP17 Gene Expression Towards Imbalance of Estrogen and Progesterone Hormones at Luteal Phase in Marriageable Girls

  • Author:
  • Suriani Bahrun1,2, Suryani As'ad3, Wardihan Sinrang4, Ilhamjaya Patellongi4, Herlianty5, Ferawati Taherong5, Nasrudin Andi Mappaware6
  • Total Page Count: 7
  • Page Number: 1135 to 1141

1Postgraduate Doctoral Program, Faculty of Medicine, Hasanuddin University, Makassar

2Nursing Program, STIK GIA Makassar, Makassar

3Department of clinical Nutrition, Faculty of Medicine, Hasanuddin University, Makassar

4Department of Physiology, Faculty of Medicine, Hasanuddin University, Makassar

5Midwifery Program, STIK GIA Makassar, Makassar

6Faculty of Medicine, Moslem University of Indonesia, Makassar

Online published on 21 February, 2019.

Abstract

Menstruation process occurs on marriageable girls as an indication that ovary has been in function. One of the menstruation phases is known as luteal phase. At this phase, a kind of problems sometimes happens, like imbalance of estrogen and progesterone hormones. Both are steroid hormones. CYP17 is a crucial enzyme for biosynthesis of steroid.

To identify the roles of CYP17 gene expression towards imbalance of estrogen and progesterone hormones at luteal phase in marriageable girls.

Adopting non-experimental design using cross sectional approach to 40 samples.

There is role between CYP17 gene expression and estrogen hormone levels. There is role between CYP17 gene expression and progesterone hormone levels. There is role between CYP17 gene expression and imbalance of estrogen and progesterone hormone.

Keywords

CYP17, estrogen, progesterone, marriageable girls