Antifungal Sensitivity of Candida Sp. Isolated from Skin Infections at a Tertiary Care Teaching Hospital

In this study, we have found the prevalence Candidal Sp. in skin infections of the patients attending at the department of medicine and Skin and VD. We have also evaluated the drug sensitivity patterns of identified Candida sp.

This prospective, cross-sectional study was conducted at the IMS and SUM hospital from January 2016 to February 2017, and comprised the causative organisms foe skin infections. Species differentiation was confirmed by specific culture medium method. Antifungal susceptibility of isolated Candida species were evaluated with disc diffusion method.

of the 219 Candida isolates, majority of them were isolated from the department of skin and VD 78(35.6%) and Medicine department 59(26.9%). Moreover, 144(65.8%) samples were of females and 75(34.2%) were of males. Candida albicans 128(58.45%) was the most predominant species followed by Candida glabrata 30(13.69%), Candida tropicalis 26(11.87%), Candida krusei 17(7.76%), Candida parapsilosis 12(5.47%), Candida dubliniensis 3(1.37%) and Candida lusitaniae 3(1.37). All isolates were least susceptible to amphotericin B with a susceptibility rate of 213(97.26%). The highest resistance was found for voriconazole 40(18.26%) compared to fluconazole 32(14.61%).

Candida species were resistant to many antifungals and in this study it is revealed that Amphotericin B is the most sensitive antifungal for skin infections.