1Department of Otorhinolaryngology, Head-Neck Surgery, Hasanuddin University, Makassar, Indonesia
2Department of Pathology Anatomy, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
*Corresponding author: Sofiatun Nurhuda Putri, Department of Otorhinolaryngology, Head-Neck Surgery Faculty of Medicine, Hasanuddin University, Perintis Kemerdekaan Km.11, Tamalanrea, Makassar (90245) Indonesia, Email: sofiatun.nurhuda@gmail.co.id
Online published on 23 December, 2019.
This study aimed to ascertain the association between inflammatory response in chronic rhinosinusitis with polyp and without polyp based on IL-8, eosinophil, and neutrophil observation.
The study was conducted on 20 chronic rhinosinusitis patients with polyp and 20 chronic rhinosinusitis patients without polyp. Examination of IL-8 level was done by using ELISA method, while eosinophil and neutrophil cell examination was done by using nasal cytology.
Of the 20 patients with chronic rhinosinusitis with polyps and 20 patients without polyps, IL-8 levels were significantly increased in patients with chronic rhinosinusitis without polyps. Meanwhile, in nasal cytology examination, eosinophil cells increased dominantly in chronic rhinosinusitis patients with polyps, while neutrophil cells increased dominantly in chronic rhinosinusitis patients without polyp (p<0.05).
There were difference of IL-8 level and eosinophil, neutrophil cells between chronic rhinosinusitis with polyp and without polyp.
IL-8, eosinophil, neutrophil
