Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 10

The Relationship between Postmenopausal Women and Some Hormonal Changes

1College of Education of Pure Science, University of Al-Muthanna, Iraq

*Corresponding Author: Kadhem Mohammed Sabae, College of Education of Pure Science, University of Al-Muthanna, Iraq, Phone: 07821771099, Email: dr.kadhemajalr98@98gmial.com

Online published on 23 December, 2019.

Abstract

Menopause is defined as loss of ability of ovarian follicles to develop. The period of menopause is affected by age and genetic factors. Also, toxic factors can affect ovarian activity such that women who smoke have earlier menopause. The irregular menstrual cycle is the most characteristic of menopause that the ovary never responds to the pituitary gland stimulation. Current study was aimed to estimate blood levels of estradiol, cholesterol, triglyceride, ALT and AST in postmenopausal women.

The present study included 120 postmenopausal women their ages ranged from 46 to 65 years and divided into two groups; 46–55 years and 56–65 years. In addition, 30 before menopausal women were recruited as a control group.

The result showed a significant increase (p<0.05) in estradiol level in all postmenopausal women compared with control group. Also, results showed a significant increase (p<0.05) in cholesterol and triglyceride levels in all postmenopausal women compared with control group. The results of ALT and AST revealed a significant increase (p<0.05) in all postmenopausal women compared with control group.

According to the results of current study, we can conclude that postmenopausal age is associated with a decrease of estradiol hormone, an increase in cholesterol and triglycerides levels, and significant differences in AST and ALT levels.

Keywords

Postmenopause, cholesterol, GPT, triglyceride, estradiol