1Department of Biology, Collage of Science, University of Kirkuk, Iraq
2Environmental Research Unit, Collage of Science, University of Kirkuk, Iraq
Polycystic ovarian syndrome is a common endocrine disorder affects women in reproductive age. The inflammatory markers play an important role in this disease. Therefore, this study was aimed to evaluate the hematological, some biochemical and serum levels of C3 in women with polycystic ovary syndrome compared with healthy women.
Hematological parameters, lipid profile and complement protein C3 serum levels, were evaluated in 60 women (30 obese and 30 lean) women with Polycystic ovarian syndrome whose age ranged between (17–43 years), in addition to 30 healthy women as controls. The patients attended Azady Teaching Hospital in Kirkuk city, Iraq for diagnosis and treatment during the period from September 2017 to March 2018.
Analyzing the collected data, we observed significant increase in total white blood cells, monocytes, lymphocytes count, and serum level of complement protein C3 in women with Polycystic ovarian syndrome compared to control subjects (
This study suggested that changes in inflammatory markers in women with Polycystic ovarian syndrome predispose them to increased risk of type 2 diabetes mellitus and cardiovascular events. Raised thyroid stimulating hormone suggested a possible role of thyroid dysfunction in the pathogenesis of Polycystic ovarian syndrome.
Polycystic ovarian syndrome, Hematological parameters, Lipid profile, Complement protein C3, TSH
