1Department of Pediatric & Preventive Dentistry, College of Dentistry, University of Baghdad, Iraq
Demineralization initiated by acids is occasionally resulting from the intake of liquid medicines used to treat children on regular basis. Fluoride and nano-Hydroxyapatite has been broadly utilized in remineralization of erosive lesions.
To compare the efficacy of nano-Hydroxyapatite with sodium fluoride on enamel surface of primary teeth after exposure to pediatric liquid medications by investigating the topographical and weight changes.
Thirty posterior primary teeth were extracted from (3–6) years old children. They were assigned to three groups: (A) nano-Hydroxyapatite, (B) sodium fluoride, and (C) artificial saliva (control). Groups A and B were exposed to pediatric liquid medications including: (Cephalexin and ParAzar). Afterwards, they were treated with 1% nano-Hydroxyapatite suspension and 2% sodium fluoride solution. The samples were examined for changes in surface roughness and weight using Atomic Force Microscope and an electronic balance respectively; at three periods: baseline, after 7 days of exposure to liquid medications, and 1 day of exposure to treatment agents.
Group A showed a highly-significant difference in roughness for subgroups treated with nano Hydroxyapatite. A highly-significant increase in roughness was noticed for Cephalexin between baseline and treatment periods and a highly-significant reduction between baseline and ParAzar exposure periods. Regarding weight, a highly-significant difference was found for Cephalexin, and a significant difference for ParAzar after nano-Hydroxyapatite treatment.
1% nano-hydroxyapatite suspension had the greatest remineralization efficacy when compared with 2% sodium fluoride solution.
Nano-Hydroxyapatite, Sodium Fluoride, Cephalexin, ParAzar, Atomic Force Microscope
