Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 10

Detection of Bioactive Compounds of Celosia argentea Using Fourier-transform Infrared Spectroscopic Profile and Evaluation of its Anti-fungal Activity

1Department of Biology, College of Science for Women

2College of Pharmacy, College of Nursing, University of Babylon, Hillah city, Iraq

3Biomedical Science Department, College of Nursing, University of Babylon, Hillah city, Iraq

*Corresponding Author: Imad Hadi Hameed, Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq, Phone: 009647716150716, Email: imad_dna@yahoo.com

Online published on 23 December, 2019.

Abstract

Celosia argentea is a smooth annual herb type plant and routinely used as leafy vegetable in the rainforest zone of Africa. In India and China, it is known as a troublesome weed. It is a herbaceous plant and is known for its very bright colors and traditional uses. This is plant of tropical origin; they grow best in full sunlight and should be placed in a well-drained area. The purpose of our research were analysis of the bioactive chemical compounds of selected medicinal plant of Celosia argentea using fourier transform infrared spectrophotometer analysis. Seven bioactive compounds were identified in the methanolic extract of Celosia argentea. The Fourier transform infrared spectrophotometer analysis of Celosia argentea proved the presence of functional group assignment Alkenes, Alkyl halides, Amide, and Alkane with Intensity 70.097 (Strong), 79.917 (Strong), 65.933 (Strong), 83.395 (Strong), 73.966 (Bending), 87.917 (Strong), 83.461 (Strong) and Peak (Wave number cm-ˡ) 667.37, 794.67, 1020.34, 1236.37, 1631.78, and 2854.65. In the current study, the anti-fungal activity of Celosia argentea methanolic extract was evaluated by determining the zone of inhibition against fungi. Celosia argentea was very highly active against Aspergillus fumigatus (4.98 ± 0.18).

Keywords

Anti-Fungal Activity, FT-IR analysis, Celosia argentea