1Professor and Head, Department of Public Health Dentistry, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India
2Reader, Department of Public Health Dentistry, Terna Dental College, Nerul, Navi Mumbai, Maharashtra
3Associate Professor, Department of Dentistry, Chamarajanagar Institute of Medical Sciences, Chamarajanagar, Karnataka
4Senior Lecturer, Department of Pedodontics, Terna Dental College, Nerul, Navi Mumbai, Maharashtra
5Reader, Department of Public Health Dentistry, Pacific Institute of Medical Sciences, Bedla, Udaipur, Rajasthan
6Reader, Department of Public Health Dentistry, Pacific Dental College and Hospital, Airport Road, Debari, Udaipur, Rajasthan, India
*Corresponding Author: Dr. Gayathri Ramesh, Associate Professor, Department of Dentistry, Chamarajanagar Institute of Medical Sciences, Chamarajanagar, Karnataka, e-mail: amug3r@gmail.com
Online published on 27 March, 2020.
This study assessed the antimicrobial potential and Minimum Inhibitory Concentration (MIC) of Moringa oleifera leaves and fruit extracts in contradiction to common periodontal pathogens. Agar well diffusion technique was used to evaluate the ethanol and petroleum ether extracts against Porphyromonas gingivalis and Prevotella intermedia. Analysis of Variance (ANOVA) and t-test were used for statistical analysis. All the extracts showed powerful antimicrobial action with MIC values fluctuating from 0.2–0.8 μg/ml against P. intermedia. Least MIC values of 0.2μg/ml against P. intermedia was observed in ethanol and petroleum ether fruit extracts. All extracts showed zone of inhibition that were statistically significant (p<0.05) at highest concentration (75 μg/ml) against P. gingivalis. Extracts of leaves and fruit of Moringa oleifera were found to be effective and contain compounds with therapeutic potential against Porphyromonas gingivalis and Prevotella intermedia.
Agar, plant extracts, Moringa oleifera, Porphyromonas gingivalis, Prevotella intermedia
