Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 11

Chemotherapy in Head and Neck Squamous Cell Carcinoma: An Overview

  • Author:
  • Sachitananda Meher1,, Santosh Kumar Subudhi2, Stithaprajna Lenka2, Aditi Ava Rath1, Waseem Alam1, Radha Prasanna Dalai3
  • Total Page Count: 5
  • Page Number: 275 to 279

1Post Graduate Trainee, Department of Oral & Maxillofacial Surgery, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

2Professor, Department of Oral & Maxillofacial Surgery, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

3Senior Lecturer, Department of Public Health Dentistry, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

*Corresponding Author: Sachitananda Meher, Post Graduate Trainee, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India, e-mail: sachin.meher007@gmail.com

Online published on 27 March, 2020.

Abstract

The term, Head and neck cancer comprises a heterogeneous group of malignancies spreading from the lips to the cervical oesophagus, with squamous cell carcinoma illustrating the ultimate ubiquitous histology. Treatment strategies are designed according to disease stage, sites of primary tumour, patient's age, operability conditions and performance status. Management approaches include surgery, chemotherapy, radiation therapy, brachyor external beam or combination of these therapy. The use of chemotherapy in head and neck squamous cell carcinoma has expanded considerably in past several years. This article summarizes the current evidence that guide the use of chemotherapy for advanced disease, unresectable tumour or unwilling patients to undergo surgery.

Keywords

Chemotherapy, Head & Neck Cancer, OSCC