1Intern, Institute of Dental Sciences, Siksha ‘O'Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India
2Reader, Department of Periodontics & Oral Implantology, Institute of Dental Sciences, Siksha ‘O'Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India
*Corresponding Author: Dr. Manoj Kumar, Reader, Department of Periodontics & Oral Implantology, Institute of Dental Sciences, Siksha ‘O ’Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India, e-mail: manojkumar@soa.ac.in
Online published on 27 March, 2020.
Periodontitis is a chronic inflammatory disease of the periodontium resulting from the pathogenic bacteria which are present in the plaque biofilm. Excessive reactive oxygen species plays an important role in the pathogenesis of periodontal disease. Increased polymorphonuclear count and activity is a reason for high rate of REACTIVE OXYGEN SPECIES(ROS) release which in turn leads to oxidative stress in periodontal tissues. Antioxidants(AO's) are the substance present at low concentrations which retards the oxidative stress. As Reactive oxygen species and Antioxidants are in active harmony so any disturbance in one would cause change in the latter. This review will be solely focused on the role of ROS, AO's and oxidative stress in causing periodontitis.
Periodontitis, Reactive Oxygen Species, Antioxidants
