Department of Biology, College of Basic Education, University of Wassit, Iraq
Online published on 27 March, 2020.
The present study was carried out to investigate the protective role of Urticadioicaleaf extract on the hormonal profile in sodium fluoride exposed female rats. Thirty two mature female rats were randomly divided to four equal group and treated for 4th weeks as follows: control group administered tap water; group T1 administered tap water containing 100 ppm NaF; group T2 administered tap water containing 100 ppm NaF plus 300 mg/kg Urticadioicaleaf extract; group T3 administered 300 mg/kg Urticadioicaleaf extract only. Blood sample were obtained at zero and 28 days of the experiments for estimation of serum progesterone, estrogen, FSH, LHconcentration. The result revealed significant decrease in serum progesterone, estrogen, FSH, LH concentration in group T1 (NaF treated group). On the other hand, the result showed the beneficial effects of Urticadioica leaf extract to improvement the previous parameters against NaF(T2), through a significantincrease in hormonal profile concentration. Therefore, it could be conclude that Urticadioicaextract has a potent ameliorative effects on hormonal profile in NaF stressed rats.
Hormonal profile, sodium fluoride, urticaleaf, rats