Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 11

Synthesis, Characterization and Antimicrobial Activity of Pd(II) and Cu(II) Complexes of Schiff base Derived from Phenylethyl amine

1Department of Physiology, Pharmacology and Chemistry, College of Veterinary Medicine, University of Basrah, Iraq

2Department of Anaesthesia, College of Health and medical technology, Middle Technical University, Baghdad, Iraq

3Department of Microbiology, College of Veterinary medicine, University of Basrah, Iraq

Online published on 27 March, 2020.

Abstract

Condensation of phenyl ethyl amine with 2-Hydroxy-3-naphthaldehyde yielded Schiff base derivative in good yield. Palladium and copper were selected for preparation of complexes. The structures of new compounds were assigned by FTIR and 1H NMR spectroscopy. The synthesized compounds were tested for their antibacterial activity against Staphylococcus aureus, Escherichia coli, Bacillus cereus, and Klebsella pneumonia. Additionally, they evaluated for their antifungal activity against Candada albicans, Candada trobicalis, candida krusi, Aspergillus multi, and Aspergillus niger. All compounds revealed significant antibacterial and antifungal activity.

Keywords

Phenylethyl amine, 2-Hydroxy-3-naphthaldehyde, Schiff base, Microbial activity, HSQC-NMR