1Associate Professor, Laboratory of Vascular Physiology and Medicine Department of Physiology
2Professor, Laboratory of Vascular Physiology and Medicine, Department of Physiology
3Professor, Department of Medicine, Shri B.M. Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, Karnataka, India
Online published on 27 March, 2020.
Cardiovascular disease (CVD) is the one of the major cause of morbidity and mortality. Experimental studies have demonstrated physiological functions of vitamin D metabolites on cardiomyocytes and endothelial and vascular smooth muscle cells. In view of a complex scenario to understand cardiac disorders linking with vitamin D the currentstudywasundertaken oncardiac patients of MI and IHD.
The cross sectional study was conducted on patients who were suffering fromcardiovascular disease (CVD). Study included 150 CVD patients (age 18 to 79 years)who wereadmitted in ICCU of a tertiary care hospital.). Patients were divided in to two groups namely myocardial infarction(MI) group 1(n=75) and ischemic heart disease (IHD) group 2 (n=75).Anthropometric, physiological and biochemical parameters were measured using standard techniques. Data was expressed as mean ± Standard Deviation (mean ± SD). The level of statistical significance was observed at P<0.05, P<0.01 using SPSS software 16.0.
There is increase in the blood pressure mainly mean arterial pressure in both MI and IHD patients. Biochemical parameters which shows normal levels of serum sodium, potassium and creatinine, higher levels of CPK-MB and reduction in serum calcium and vitamin D of both MI and IHD patients compared to normal recommendedvalues although these values are not statistically significant between MI and IHD patients.
The significant role of vitamin D for calcium homeostasis may be considered as important marker for assessment of severity and morbidity of MI and IHD.
Cardiovascular disease, serum calcium, vitamin D
