1Intern, Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India
2Reader, Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India
*Corresponding Author: Dr. Abhaya Chandra Das, Reader, Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India, e-mail: drabhaya2011@gmail.com
Online published on 27 March, 2020.
The periodontal diseases are usually complex and multifactorial, and causes a loss of connective tissue attachment. Thus, regenerating the lost periodontal tissues becomes an important part of the therapy. Procedures such as bone grafts, Guided tissue regeneration (GTR), root biomodifications are routinely used to achieve regeneration but their success rates are limited. Platelets have an important role in regenerating the lost periodontal structures since they release growth factors when they come in contact with damaged tissues. Platelet rich plasma (PRP) and Platelet rich Fibrin (PRF) are platelet concentrates which can be obtained from patient's own blood. Choukroun's PRF is a natural biomaterial which is fibrin based and prepared without any addition of anticoagulant. The slow polymerization speed used during centrifugation renders it to be a better healing material. This article reviews the preparation of PRF and the efficacy of using it in regeneration of various periodontal structures.
Centrifugation, healing, platelets, platelet rich fibrin, regeneration
