Intern,
Various studies were performed to understand the molecular basis of the host microbial interaction. It is the interaction of the microorganisms with the host which determines the course and extent of the periodontal disease. Entry of bacteria itself or bacterial products into the tissues may be important in the disease process and to evade the host defence mechanism. Periodontal diseases such as gingivitis and periodontist are common inflammatory disorders caused by microbiota inhabiting the plaque. This paper highlights the various interaction courses which leads to progression of periodontal disease. It can be stated as a multifactorial disease as collective interactions of etiological agents and host responses along with environmental factors play an important role in the onset and progression of the disease.
Periodontal disease, Bacteria, Host defence