Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 11

Vesiculobullous Lesions: A Comprehensive Overview

  • Author:
  • Saswati Priyadarshini1, Sanat Kumar Bhuyan2, Rajat Panigrahy3, Pinali Das4, Shayari Niyogi5
  • Total Page Count: 5
  • Page Number: 933 to 937

1Post-Graduate Trainee, Department of Oral Medicine and Radiology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

2Professor, Department of Oral Medicine and Radiology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

3Reader, Department of Oral Medicine and Radiology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

4Post-Graduate Trainee, Department of Oral Medicine and Radiology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

5Post-Graduate Trainee, Department of Oral Medicine and Radiology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

Online published on 27 March, 2020.

Abstract

Vesiculobullous lesions are defined as a form of muco-cutaneous diseases in which both vescicles and bullae are evident. ‘Vesiculobullous’ sometimes termed as ‘Immunobullous'as decreased immune system of the body causes these diseases. These are either result of range of infections, decreased immunity, drug-induced, hereditary or caused by mechanical injury. In all cases ulcerations occur due to rupture of lesions which will further make the diagnosis of lesions difficult to make. This overview will provide a knowledge about the vesiculobullous lesions along with the characteristic's features affecting the mouth, complete etiopathogenesis, site of occurrence of lesions along with their recent advances in the identification of these lesions. This will also aid in differentially diagnosing the lesions which exhibit similar sign asvesiculobullous lesions but the histopathological examination and immunofluorescence lead to the definitive diagnosis of the lesions.

Keywords

Steven-Johnsons Syndrome, Toxic Epidermal Necrolysis, Oral Lichen Planus, Erythema Multiforme, Mucous Membrane Pemphigoid, Pemphigus Vulgaris