Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 11

Carcinogenesis: A Comprehensive Overview

1Associate Professor, Department of Prosthodontics, Siksha ‘O'Anusandhan (Deemed to be University), Bhubaneswar, Odisha

2Associate Professor, Department of Oral Medicine & Maxillofacial Radiology, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

3Researcher, Karolinska Institute College and University, Stockholm, Sweden

*Corresponding Author: Smita R. Priyadarshini, Reader, Department of Oral Medicine & Maxillofacial Radiology, Siksha ‘O ’Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India, e-mail: smitapriyadarshini@soa.ac.in

Online published on 27 March, 2020.

Abstract

Carcinogenesis is the process of tumor induction which occurs by the oncogenes which signal the molecules at various stages of growth. Apoptosis also leads to membrane dissolution of nucleus and cytosolic skeleton, chromosome degradation and fragmentation of nucleus. Even presence of various chemical, viral, radiation carcinogens that enhance carcinogenesis. In this article we have elaborated factors & process leading to carcinogenesis.

Keywords

Oncogenes, Host Defense, Pathogenesis