1Clinical Tutor, Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha ‘O’ Anusandhan (Deemed to be University)
2Senior Lecturer, Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha ‘O’ Anusandhan (Deemed to be University)
3Post Graduate Trainee, Department of Public Health Dentistry, Institute of Dental Sciences, Siksha ‘O’ Anusandhan (Deemed to be University), Clinician, Bhubaneswar, Odisha, India
4Professor, Institute of Dental Sciences, Siksha ‘O’ Anusandhan (Deemed to be University)
*Corresponding Author: Dr. Gatha Mohanty, Senior Lecturer, Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India, e-mail: gatha.mohanty@gmail.com
Online published on 27 March, 2020.
Dental Enamel forms the outermost covering of teeth. Being the hardest mineralized tissue of human body, it is subjected to many challenges such as demineralization and remineralization to maintain an integrity within the oral environment. It is also prone to wear, decay and damage. However, it cannot regenerate as its origin is from the cells lost after a tooth is erupted. Restoration of lost enamel is possible by use of conventional treatment that uses synthetics, however it is impossible to mimic the natural prototype. Clear understanding and recent advances in material science has paved a way in formation of synthetic enamel. Isolation of post natal stem cells and understanding the interactions of proteins and their genetic products has led to development of materials that are smart that can be useful in cell and growth factor delivery. This article highlights the recent trends in bio-mimetic synthesis and strategies that's are cell based and make enamel regeneration possible and the various obstacles that needs to be overcome before it is available to dental practitioners.
Regeneration, Enamel, Tissue Engineering
