1Department of Pharmacology, Faculty of Pharmacy, Al-Kafeel University, Najaf
2Department of Physiology, Faculty of Medicine, Thi-Qar University
3College of Pharmacy, Telafer University
4Department of Urology, Faculty of Medicine, Kufa University
5College of Health and Medical Technology, University of Al-Ayen, Thi-Qar
6Specialized Dental Center Sumer, Thi-Qar Health Directorate, Thi-Qar, Iraq
*Corresponding Author: Saad Mashkoor Waleed Al-Zaiyadi, Department of Pharmacology, Faculty of Pharmacy, Al-Kafeel University, Najaf, Iraq, e-mail: saad.alzaiy@alkafeel.edu.iq, alibadr205@gmail.com
Online published on 27 March, 2020.
Fifty subfertility couples were involved in the present study during their attendance at the fertility clinic at Al-Sadder teaching hospital in Al-Najaf/Iraq throughout a period from January 2018 to January 2019 to undergo intracytoplasmic sperm injection (ICSI). Details history and physical examination were done for every subject participated in this study. Fertilization rate (FR) was calculated as percentage transformation of microinjected oocytes into two pronuclei. A categorical variable of FR defined based on 50% FR grouped couples; Group I with FR>50% and Group II with FR>50%. The objective of this study was to investigate the influence of fertilization rate on ICSI outcome and pregnancy rate for unexplained subfertile couples. Main results of this study revealed that there was a significant difference (p<0.05) in ICSI outcome and pregnancy rate between different study groups. With increasing fertilization rate, there was an increase in the ICSI outcome and the pregnancy rate. It was concluded that increased fertilization rate have a positive impact on the ICSI outcome and pregnancy rate for unexplained subfertile couples.
Intracytoplasmic sperm injection, Fertilization, Fertilization rate
