1Lecturer, Baghdad Medical City Campus, Ministry of Health and Environment
2Asst. Prof., Department of Pharmacy, Al-Esraa University College, Baghdad, Iraq
*Corresponding Author: Hayder Adnan Fawzi, Asst. Prof., Department of Pharmacy, Al-Esraa University College, Baghdad, Iraq, Phone No.: + 964 (0) 7800015294, e-mail: hayder.adnan2010@gmail.com
Online published on 27 March, 2020.
Study the relationship of dialysis adequacy with the effectiveness of erythropoietin for the management of anemia in hemodialysis patients.
A retrospective cohort study, conducted in the Medical city complex from January 2019 to June 2019, the study involved 162 ESRD patients on regular hemodialysis sessions.
Change in Hb (percentage and value), was significantly higher in patients receiving once-weekly erythropoietin compared to both twice and thrice and more dosing per week. Overall only 33 (21.2%) of the patients achieved target Hb (10–11 mg/dL) with 6 months of follow-up. There was an inverse significant correlation between percentage change after 6 months with baseline Hb, baseline ferritin, and baseline albumin. While with urea at baseline, number of weekly sessions, and Kt/V the relationship becomes direct and significant. There is an increased risk (2 folds) of not achieving target Hb (10–11 mg/dL) in patients with DM compared to those without DM.
Once weekly regimen appeared to superior to other regimens (twice or more per week).
Erythropoietin, dialysis, hemoglobin, anemia, weekly dosing
