1Research Scholar, Department of Anatomy, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India
2Reader, Department of Anatomy, CSI College of Dental Sciences and Research, Madurai
3Govindarajan Sumathy, Prof & HOD, Department of Anatomy, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education, Chennai
*Corresponding Author: Govindarajan Sumathy Prof & HOD, Department of Anatomy, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education, Chennai
Online published on 27 March, 2020.
Highly motile sperms with good morphology are more capable of fertilizing an oocyte and increase the pregnancy rate during the process of ART. In swim up method and density gradient method, multiple centrifugation leads to ROS production that can cause DNA damage to the sperms. Microfluidic chips are one of the Method of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation method used in sperm separation in IVF (in vitro fertilization) laboratories leads to sperm DNA fragmentation. By using microfluidics sperm sorting device, spermatozoa do not undergo such physical stress. Therefore it is possible to obtain sperms with ICSI criteria of good motility and in higher concentration with the use of micro fluidic sperm sorting device.
Sperm Concentration, Motility, Oligozoospermia, Asthenospermia, micro-fluidic sperm sorting device and ICSI
