Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 11

Role of Free Radicals in Cellular Signaling: A Review

  • Author:
  • Jayamathi Govindaraj1, Keerthidaa Govindaraj2, S. Raghavendra Jayesh3, Kesavaram Padmavathy4, U. Vidyarekha5
  • Total Page Count: 4
  • Page Number: 2799 to 2802

1Professor, Department of Biochemistry, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Pallikaranai

2MDS Department of Periodontics, Thai Mookambihai Dental College And Hospital, MGR University, Maduravoyal

3Professor, Department of Prosthodontics, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, (BIHER), Pallikaranai

4Associate Professor, Department of Microbiology, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Pallikaranai

5Senior Lecturer in Public Health Dentistry, Sree Balaji Dental College & Hospital, Bharath institute of Higher education and Research, Pallikaaranai, Chennai

Online published on 27 March, 2020.

Abstract

Reactive oxygen species (ROS) were once considered to be deleterious agents, contributing to a vast range of pathologies. Both their damaging and beneficial effects are initiated when they target distinct molecules and consequently begin functioning as part of complex signal-transduction pathways. The recognition of ROS as signaling mediators has driven a wealth of research into their roles in both normal and pathophysiological states. The present review assesses the outline of current perspectives on redox-signaling mechanisms.

Keywords

Reactive oxygen species, oxidative stress, nitric oxide