1Professor, Department of Biochemistry, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Pallikaranai
2MDS Department of Periodontics, Thai Mookambihai Dental College And Hospital, MGR University, Maduravoyal
3Professor, Department of Prosthodontics, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, (BIHER), Pallikaranai
4Associate Professor, Department of Microbiology, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Pallikaranai
5Senior Lecturer in Public Health Dentistry, Sree Balaji Dental College & Hospital, Bharath institute of Higher education and Research, Pallikaaranai, Chennai
Online published on 27 March, 2020.
Adipocytokines are mainly adipocyte-derived cytokines regulating metabolism and are key regulators of insulin resistance. Visfatin is a newly discovered adipocyte hormone with a direct relationship type 2 diabetes mellitus. Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is a protein with diverse functions. Although the first discovery of this molecule as a pre-B-cell colony-enhancing factor suggested primarily a cytokine function, its rediscovery as the key enzyme in nicotinamide adenine dinucleotide generation has considerably widened its potential biological activities. Its broad spectrum of effects is being regarded as a potential approach to prevent and treat various pathological conditions.
Adipose tissue, adipokines, quinolinc acid, insulin resistance
