1Post Graduate, Department of Oral and Maxillofacial Surgery, Sree Balaji Dental College and Hospital, Velachery Main Road, Narayanapuram, Pallikaranai
2Professor, Head of the Department of Oral and Maxillofacial Surgery, Sree Balaji Dental College and Hospital, BIHER
3Professor, Department of Oral Maxillofacial Surgery, Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamilnadu, India
*Corresponding Author: Dr. Chandhini Asokan, Post Graduate, Department of Oral and Maxillofacial Surgery, Sree Balaji Dental College and Hospital, Velachery Main Road, Narayanapuram, Pallikaranai, Chennai-600100, Tamil Nadu, Telephone No.: 9710349436, e-mail: chandhini.92@gmail.com
Online published on 27 March, 2020.
A systematic review of the literature was undertaken examining data to find the evidence of prophylactic administration of antibiotics inrelation to treating patients of maxillofacial fractures.
Studies that fulfilled most of the requirements pertaining to it were retrieved. A computerized search was carried out using PubMed, and MEDLINE databases with the logical operators: “antibiotic” and “prophylaxis” and “maxillofacial trauma.”
A survey of these studies showed a drastic decrease in the infection rate of mandibular fractures in the antibiotic treated groups when being compared with the control groups. A variety of antibiotics had been used with an apparently constant effect. An“once a day”regimen ora1-day treatment course had a similar or perhaps even better result than 7 days of treatment. No infections were corresponding to condylar, maxillary, or zygomafractures.
An “once a day” regimenor 1-day administration of prophylactic antibiotics seem to be the best documented to reduce infections.
Antibiotics, Fracture, Prophylaxis