1Lecturer, Department of Orthodontic, Pedodontic and Preventive Dentistry, College of Dentistry, Iraq, Mustansiyriah University
2Assistant Professor, Department of Orthodontic, Pedodontic and Preventive Dentistry, College of Dentistry, Iraq, Mustansiyriah University
3Assistant Lecturer, Department of Orthodontic, Pedodontic and Preventive Dentistry, Dentistry Department Dijlah University, Iraq
Online published on 27 March, 2020.
Saliva has been suggested as a non-invasive diagnostic fluid that may be used in the diagnosis of oral and systemic diseases. The salivary levels of IL-17 could be used as a substitute to distinguish periodontal healthy from periodontitis subjects. Therefore, the goal of the present investigation was to determine if the levels of IL-17 in saliva would differ between a group of periodontal healthy and periodontitis subjects. Correlations between the concentration of IL-17 and clinical parameters of periodontal disease were also examined.
Unstimulated saliva was collected from each individual (24 patients with periodontitis and 24 healthy age-and gender-matched individuals as control group). Salivary interleukin 17 level was evaluated for both groups using enzyme-Linked Immuno-sorbent assay technique.
Mean values of IL-17 levels were highly significantly increased in patients with chronic periodontitis patients as compared to healthy control subjects.
Interleukin 17 has special importance could be used as a positive predictive factor for prediction and diagnosis of periodontitis.
IL-17, ELISA, periodontitis, saliva, biomarkers
