Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 11

In Vivo Effect of Levan Purified from Leuconostoc Mesenteroides ssp. Cremoris Against Candida Albicans

1Department of Biology, College of Sciences, Mustansiriyah University, Baghdad, Iraq

Online published on 27 March, 2020.

Abstract

Toxicity of levan purified from Leuconostoc mesenteroides ssp. cremoris on mice was studied, and observed that no death of mice was recorded at 100 mg/ml, also antagonistic activity of levan against C. albicans In vivo was determined with histological study on small intestine and liver tissue of mice, and the results showed that the levan had the ability to treat the infected tissue with C. albicans also had less damage to the tissue compared with the fluconazole.

Keywords

Levan polymer, Leuconostoc mesenteroides, Candida albicans, Toxicity, Histological study