1Post Graduate Student, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research
2Professor, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research
3Post Graduate Student, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research
4Reader, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research
5Professor and Head of the Department Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research
*Corresponding Author: Dr. Sangeetha Priya P. Post Graduate Student, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Phone: 9884770609, Email: Sangeethapriya.omfp@gmail.com
Online published on 27 March, 2020.
On focus with route of drug administration, the oral cavity is an attractive and the safest site for the delivery of drugs. As an advantage it can overcome acidic environment thereby causing instability of the drug, extensive first pass metabolism and low bioavailability of drug results an inadequate absorption. The buccal mucosa is rich in blood supply and relatively permeable. Buccal cavity was found to be most accessible site for both local and systemic delivery of drug. This review presents a brief description of advantages and limitations of oral mucosal drug delivery, mechanisms of drug permeation followed by current developments in this drug delivery systems.
Drug, Buccal, Sublingual
