1Post Graduate Student, Sree Balaji Dental College and Hospital, BIHER, Department of Periodontics and Implantology, Velachery Main Road, Pallikaranai, Chennai, Tamil Nadu, India
2Professor, Sree Balaji Dental College and Hospital, BIHER, Department of Periodontics and Implantology, Velachery Main Road, Pallikaranai, Chennai, Tamil Nadu, India
3Head of the Department Sree Balaji Dental College and Hospital, BIHER, Department of Periodontics and Implantology, Velachery Main Road, Pallikaranai, Chennai, Tamil Nadu, India
4Reader, Sree Balaji Dental College and Hospital, BIHER, Department of Periodontics and Implantology, Velachery Main Road, Pallikaranai, Chennai, Tamil Nadu, India
*Corresponding Author: Dr. Nithya Anand, MDS Professor, Sree Balaji Dental College And Hospital, Department of Periodontics and implantology, Velachery Main Road, Pallikaranai, Chennai, 600100, Tamil Nadu, India, Email: Nitan10@gmail.com
Online published on 27 March, 2020.
Chronic kidney disease (CKD) is a veryreal and growing problem, as indicated by demographic trends. Presence of undiagnosed periodontitis may have significant effect on the medical management of CKD patient as its been found to contribute to systemic inflammatory burden. This study evaluate and compare the periodontal status and IL-6 levels among CKD, periodontitis and Healthy patients.
Whole serum samples werecollected from 80 patients who were further divided into four groups; healthy(n=20), periodontitis(n=20), HD(n=20), PD(n=20). Serum IL-6 concentrations were determined by Standard enzyme-linked immunosorbent assay.
Indicates the IL-6 levels in the studypopulation. The mean IL-6 value being highest in pre-dialysis (92.695) compared to dialysis(53.112), periodontitis (9.22) and healthy individuals (9.6).ANOVA results show a significant increase of IL-6 levels in the pre-dialysis group compared to alter groups. No significant change on PPD was appreciated.
Treatment of moderate to severeperiodontitis in ESRD populations will result in decreased IL-6 levels and, more importantly, decreased incidence of atherosclerotic complications awaits the result of interceptive clinical trials in this population
Chronic renal disease, Periodontitis, interleukin 6, End stage renal disease, dialysis, Periodontal status
