1Undergraduate Student, Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University, Chennai, Tamilnadu, India
2Professor, Department of Pedodontics & Preventive Dentistry, Saveetha Dental College, SIMATS, Saveetha University, Chennai, Tamilnadu, India
3Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Saveetha University, Chennai, Tamilnadu, India
*Corresponding author Dr. Lakshmi Thangavelu, Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha University, Chennai, Tamilnadu, India. Email: Lakshmi@saveetha.com
Online published on 27 March, 2020.
To analyse the COX2 inhibitory activity of Abutilon indicum.
The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum
Prostaglandins are important mediators of the body's response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms-COX-1 and COX-2. Abutilon indicum, commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial.
Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits.
Ethnomedicinal, anti-arthritic, COX2 Inhibition, medicinal uses, Prostaglandin
