1Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
2Researcher, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
3 Senior Lecturer, Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
4Researcher, Department of Biotechnology, School of Biosciences and Technology, VIT, Vellore, Tamil Nadu, India
*Corresponding author: Dr S Rajeshkumar Associate Professor, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India, Mob: +91 9629739263, E-mail: ssrajeshkumar@hotmail.com,
Online published on 27 March, 2020.
Biosynthesis of metallic nanoparticles for its medical applications has become a major focus in nanotechnology in the recent years. Aloe vera has a wide spectrum of medicinal applications due to its anti-inflammatory, antimicrobial, anticancer and wound healing properties. Copper oxide nanoparticles have effective antimicrobial action against a wide range of pathogens and also dug resistant bacteria.
In the present study, Aloe vera gel is used to synthesize copper oxide nanoparticles and were characterized using UV-visible spectrophotometry and FT-IR. The anticariogenic activity of oral pathogens namely, Staphylococcus. aureus, Streptococcus mutans, Enterococcus faecalis, Pseudomonas sp, were also tested
UV absorption spectra of the synthesized nanoparticles revealed an intense surface plasmon resonance between 250 and 300. The functional groups in the copper oxide nanoparticles were determined by FT-IR and these also shown to have potent anticariogenic activity.
Copper oxide nanoparticles synthesized using Aloe vera gel shown to have an excellent anticariogenic activity and has a wide array of dental applications.
Copper oxide nanoparticles, Aloe vera, green synthesis, anticariogenic
