1PG Student, Department of Biochemistry, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai
2Professor & Head, Department of Biochemistry, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai
3 Professor, Department of Biochemistry, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai
*Corresponding Author: Dr. B. Shanthi Professor & HOD, Professor, Department of Biochemistry, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai-73. E Mail ‘drshanthibio@gmail.com. M No-9884025026
Online published on 27 March, 2020.
Metabolic syndrome is a cluster of risk factors that increases the probability for developing cardiovascular disease, diabetes mellitus and chronic kidney disease. Non-alcoholic fatty liver disease is emerging as a major heath burden and is considered as the most common liver disease affecting large number of people and its prevalence is rising. It occurs in significant proportion of people who do not take alcohol.
It aims in studying the prevalence of non-alcoholic fatty liver disease in already diagnosed metabolic syndrome patients.
A total of 100 metabolic syndrome patients were selected for study over a period of 1year. The patients were selected based on the metabolic syndrome criteria as given by National Cholesterol Education Program (NCEP) adult Treatment Panel III (ATP III). General demographic data were taken and biochemical parameters were estimated by standard guideline. When the criteria for Met syndrome has been fulfilled USG abdomen were taken for these patients.
Out of 100 cases, 34 patients had USG evidence of fatty liver and out of them 18 had grade 1, 14 had grade 2 and 2 had grade 3 fatty liver. Age of the participants ranged from 20–60 yearswhere average age of the patients was 41.36 with standard deviation 7.170. BMI, waist circumference, triglyceride, fasting insulin, HOMAIR are found to be significant while HDL is not significant.
Non-alcoholic fatty liver disease is related with metabolic syndrome which is both the cause and also the consequences in the study population. Increased prevalence of all the metabolic factors and changes are seen in biochemical markers in Non-alcoholic fatty liver cases. Early diagnosis and treatment will help in preventing the complications.
Metabolic syndrome, cardiovascular disease, Non-alcoholic fatty liver disease
