1Post Graduate, Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai
2Professor, Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai
NAFLD is considered as the most common liver disease affecting large number of people. Metabolic syndrome is a group of metabolic abnormalities in which the chance of developing cardiovascular disease, diabetes mellitus, chronic kidney disease are high.
It aims to determine the potential risk categories and risk factors for developing steatohepatitis in NAFLD cases with metabolic syndrome.
Total of 100 metabolic syndrome patients were selected for study over a period of 1year. These patients were selected based on the criteria for metabolic syndrome as established by National Cholesterol Education Program (NCEP) adult Treatment Panel III (ATP III). Demographic data were taken and biochemical parameters were estimated by standard guideline.
BMI, waist circumference, systolic blood pressure, PPBS, fasting insulin, HOMAIR, total cholesterol, TGL, HDL, LDL, VLDL and CHO: HDL are p<0.05; and affecting steatohepatitis. HDL is significantly lower in steatohepatitis cases compared to non-steatohepatitis cases. Diastolic blood pressure, FBS and HbA1c are not affecting steatohepatitis as the corresponding p-values are greater than the significance level.
There is positive correlation of obesity, waist circumference, blood pressure, insulin resistance, triglyceride, fasting glucose, LDL, VLDL and negative correlation with HDL-C.
Dyslipidaemia, Lipid profile, NCEP, Metabolic syndrome
