1Department of Dental Hygiene, Hallym Polytechnic University, 48 Janghakgil, Dong-Myeon, Chuncheonsi, Gangwon-do, 24210, Republic of Korea
2Department and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea
3 Department of Dental Hygiene, Hanseo University, 46 Hanseo 1-ro, Haemi-myun, Seosan-si, Chungcheongnam-do, 31963, Republic of Korea
*Corresponding Author: Min-Kyung Kang, kmk0709@hanseo.ac.kr
Online published on 27 March, 2020.
Glycyrrhizauralensis is known for its antibacterial properties. The purpose of this study were to analyze surface characteristics of denture base resin coated with G. uralensis to evaluate antimicrobial activity and cell cytotoxicity.
The powdered G. uralensis extract was dissolved in Plaquit solution and then applied to a denture base resin and cured with light. Microhardness, water contact angle, and color change analyses were performed to analyze the surface characteristics. Specimens were obtained from the coated surfaces and analyzed to determine the amount of polyphenol. Antimicrobial activity was evaluated against S. mutansand C. albicans and cytotoxicity was investigated using the MTT assay.
The surface coated with the G. uralensis extract maintained or improved the mechanical and physical properties of the specimens. The polyphenol content increased with the amount of G. uralensis coating. The antimicrobial activity of the specimens from the experimental group showed a significant effect on both C. albicans and S. mutans compared to that from control group. In addition, denture base resins coated with the G. uralensis extract were noncytotoxic, demonstrating their biocompatibility.
Denture base resins coated with G. uralensis extracts can be used to develop antimicrobial denture base resins to prevent oral stomatitis.
Glycyrrhizauralensis, Antibacterial activity, Streptococcus mutans, Candida albicans, Denture
