Correlated Levels of Anti-Inflammatory Interleukins (IL-4 and IL-10) with Allergic Conjunctivitis (AC) in Iraqi Patients

Allergic conjunctivitis (AC) is caused by an allergic reaction, most common form was hypersensitivity reaction (type 1), that caused to perennial or seasonal AC. Current study was done in the Hospital of Ibn-AL-Hythem for eyes infections in Baghdad from September-August of 2018, one hundred and thirty-two serum were collected from allergic conjunctivitis patients after diagnostic by a specialist ophthalmologist according to have symptoms, who included 60 male and 72 female, with range age (15–51) years. Used the enzyme-linked immunosorbent assay (ELISA kit) from (Pepro-Tech Company, UK) for estimating levels of both Interleukins (IL-4 and IL-10) in patients serum

Current study showed higher significant in age group (≥ 35 years) as percentage (57.6%) compare to age group (25–35) as (28.1%), also significantly higher in females (54.5%) than males (45.5%), also level of IL-4 in allergic conjunctivitis patients was (23.91± 2.09) compare to control (21.02± 2.99), so significantly increased levels of IL-10 in allergic conjunctivitis patients (14.99 ± 2.30) than control (11.10± 1.99).

Current study were concluded higher significant of allergic conjunctivitis Iraqi patients in age group (≥ 35 years), and the AC in females higher than males, as well as level of IL-4 in allergic conjunctivitis patients were significant with control, and significantly increased levels of IL-10 in allergic conjunctivitis patients compare to control.