1Ph. D. Medical Microbiology, Department of Medical Lab, University Technical College, North Technical, Kirkuk City, Iraq
2Ph. D. Medical Microbiology, Medical Lab Consultant, Children Hospital, Kirkuk Health Directorate, Kirkuk City. Iraq
The aim of the study was to detect of human papillomavirus (HPV) in cervical mucus of women with spontaneous abortion by real-time PCR. Cervical mucus of 200 women with spontaneous abortion and 100 full term pregnant women were included in this cross-sectional which carried out in Kirkuk city-Iraq from beginning of 1st of October 2018 to the end of December 2018. HPV DNA was detected real-time PCR of genotype 16, 18 and 58 in cervical samples. The study showed that the highest rate of HPV DNA (29.5%) was detected in women with abortion comparing with pregnant women (12%) with highly significant relation of HPV with abortion (P. value: <0.05). The study stated that the highest rate of aborted women was infected with HPV 16 (37.29%) followed by HPV 58 (30.26%) while HPV 18 was found in 12.26% of those women and 13.56% of them was infected with both HPV 16 and HPV 58 genotypes. The study exhibited that 36.37% of aborted women with one time in their marriage age was infected with HPV followed by 28.995 in women with 2–3 time, the study presented that 52.5% of women with abortion was belonged to the age group 27–36 years.
Spontaneous abortion was highly associated with HPV infection specially with HPV 16 genotype.
Abortion, HPV, cervical mucus, real-time PCR
