Evaluation of Multi Drug Resistance Tuberculosis During the Study of Pulmonary TB in Telangana Population

Out of 89 adults (aged between 25 to 75 years old)of both sexes of pulmonary Tuberclosis 4 (4.4%) were multi drug TB patients detected. The 89 patients history was 24(26.9%) were Tobacco smokers, 19(21.3%) had exposed to air-pollution, 11(12.3%) had high dosage of cortico steroids, 6(6.7%) had haemodialysis, 7(7.8%) were diabetes mellitus, 8(8.9%) had alcohol use, 5(5.6%) had chronic liver diseases, 9(10.1%) were HIV positive. Reasons for discontinuation of TB treatment was, 29(32.5%) had false sense of cure, 12(13.4%) had non-co-operation of paramedical staff, 11(12.3%) had domestic problems, 14(15.7%) had migrated for labor, 9(10.1%) cost of transport, 14(15.7%) had adverse drug reactions. The rate of resistance in single and poly drug therapy was. Rifampicin, pyrozinamide, ethambutol streptomycin had 0% rate resistance. Ioniazide + streptomycin, Isoniazide + streptomycin + rifampiain, Ethambutol + streptomycin had 0.5% resistance rate. Isonizide + Ethmubutol had 2.2% rate of resistance. Isonizide had 1.8% resistance. This study of pulmonary tuberculosis with MDRTB patients with different history and different rates of immunity will be quite useful to pulmonary medicine physician to treat such patients efficiently because pulmonary tuberculosis is one of the main causes of morbidity and mortality in India and abroad.