Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 12

Efficacy of Locally Delivered 1% Metformin (MF) in Treating Periodontal Intrabony Defects: A Systematic Review

1Post Graduate Student, Department of Periodontics, Sree Balaji Dental College and Hospital

2Reader, Department of Periodontics, Sree Balaji Dental College and Hospital

3Professor and Head, Department of Periodontics, Sree Balaji Dental College and Hospital

*Corresponding Author: Dr. Keerthana S.A. Post Graduate Student, Department of Periodontics, Sree Balaji Dental College and Hospital, e-mail: keethuddon@gmail.com, Contact No.: 9790854291,

Online published on 31 March, 2020.

Abstract

Periodontitis is characterized by destruction of supporting structures of tooth and may also lead to loss of teeth if untreated. The aim of this review is to systematically evaluate the efficacy of 1% MF in the treatment of periodontitis. An electronic search was carried out using the keywords ‘metformin’, ‘periodontal’ and ‘periodontitis’ via the PubMed/Medline, ISI Web of Science and Google Scholar databases for relevant articles published from 1949 toFebruary 2019.

Keywords

Metformin, Intrabony Defects, Periodontitis, Diabetes Mellitus