1Department of Surgery, Al-Diwaniyah Teaching Hospital, Al-Diwaniyah, Iraq
2Department of Surgery, College of Medicine, University of Al-Qadisiyah, Al-Diwaniyah, Iraq
3Clinical Pharmacy Departments, Baghdad Medical City Hospitals Campus
*Corresponding author: Hayder Adnan Fawzi, Email: hayder.adnan2010@gmail.com
Online published on 8 March, 2019.
A fissure consist of crack or tear in the vertical axis of the anal canal between the anal verge and the dentate line. Anal fissure is treated by two ways either medical or surgical treatment or both.
Evaluate the healing response of topical application of nifedipine with lidocaine in acute and chronic anal fissure
A prospective study of one hundred patients presented with anal fissure to outpatient surgical clinic in Al-Diwaniyah teaching hospital, the patients divided into two groups, 40 patients (15 males and 25 females) with acute anal fissure, and 60 patients (25 males and 35 females) with chronic anal fissure.
There was no statistically significant difference in the healing rate between acute and chronic lesion, however the rate of healed lesion in acute setting is higher than that of chronic setting (80% vs. 56%)
Topical application nifedipine and lidocaine effective in treating acute anal fissures with the healing response of 85%, and prevent evolution of acute anal fissures to chronic anal fissure.
Acute, chronic, anal fissure, Medical treatment
