Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 2

Study of Humeral Immune Response and Some of the Blood Variables in Mice Balb/c Treated with LPS of Klebsiella pneumoniae Antigen and Glycyrrhiza glabra Extract

1Department of Biotechnology, College of Applied Science, University of Fallujah, Fallujah, Anbar, 31001, Iraq

2Department of Biology, College of Science, University of Anbar, Ramadi, Anbar, 31001, Iraq

3Department of Medical Laboratory Techniques, Al-Maarif University College, Anbar, 31001, Iraq

Online published on 8 March, 2019.

Abstract

In this work, lipopolysaccharides of Klebsiella pneumonia and extract of Glycyrrhiza glabra were used to investigate the humoral immunity in mice Balb/c (in vivo). In contrast, little is known about humeral immunity induced by LPS and Glycyrrhiza glabra. Some parameters were used to achieve this study, are WBC and differential count, Concentration of antibodies IgA, IgM, IgG and Concentration of complement proteins type C3 and C4/mg/100. The results showed there are a significant change in a parameters values in IgA, IgM, IgG and Concentration of complement proteins type C3 and C4, also in CBC and differentiated WBC.

Keywords

LPS, immunology, extract of Glycyrrhiza glabra, in vivo, Klebsiella pneumoniae