1Biotechnology Dept. Genetic Engineering and Biotechnology Institute for Postgraduate Studies, University of Baghdad, Baghdad, Iraq
Online published on 8 March, 2019.
Polycystic Ovary Syndrome (PCOS) exists commonly among women in the reproductive age with an incidence rate of 3–15%. The clinical manifestations of PCOS include oligomenorrhoea, infertility and obesity. There is significant overlap of symptoms between PCOS and hypercytokinemia. The aim of this study was to investigate the prevalence of hypercytokinemia in PCOS patients.
This was a cross-sectional study of clinically diagnosed 50 females with PCOS and another 50 age-matched females were studied as the control population. PCOS and Hypothyroidism were diagnosed by Ultrasound (US) and biochemical parameters IL6, TSH, T3 and T4.
The mean IL6, TSH, T3 and T4 were significantly higher in women with PCOS as compared to healthy women controls.
PCOS is on the rise in hypothyroid patients. Identification of hypothyroidism may help us to treat and prevent fertility complications in PCOS females. Hypothyroidism needs to be early corrected in the management of infertility associated with PCOS which is of major concern these days.
Polycystic Ovarian Syndrome, Thyroid Stimulating Hormone. Interleukin 6, Hypercytokinemia, Hypothyroidism
