A Comparative Study between Homocysteine, s-adenosylhomocystine and Troponin for Myocardiac Infarction Patients and the Role of Vitamin B6 and B12 in the Homocysteine Accumulation

We evaluated the correlations between serum s-adenosylhomocystine, homocysteine, vitamin B6 and vitamin B12 with the severity of MI. S-adenosylhomocystine, homocysteine, troponin, vitamin B6 and vitamin B12 from 90 acute myocardial infarction (AMI) and 120 controls were measured by ELISA technique (VIDIS for troponin), and the data were analyzed by SPSS software. The study subjects divided to four groups from onset of heart attack to blood collected into G1 group (in the same day), G2 group (in the second day), G3 group (in the third day) and G4 group (after the third day). The results of our study show a significant increase in s-adenosylhomocystine in all groups in both males and females patients, and for troponin show a significant increase just in the first three the groups in both genders and for homocysteine shown a significant increase just in the first two the groups in both genders.