Indian Journal of Public Health Research & Development
  • Year: 2019
  • Volume: 10
  • Issue: 3

Comparative Evaluation of Efficacy of Oral Diazepam and Buspirone in Reducing Anxiety and Discomfort in Mandibular Third Molar Surgery-In Vivo Study

  • Author:
  • Sushmita Mitra1, Kalyani Bhate2, S.N. Santhosh Kumar2, Kapil Kshirsagar3, Bhagyashree Jagtap4, Pradnya Kakodkar5,
  • Total Page Count: 5
  • Page Number: 182 to 186

1Consulting Oral and Maxillofacial Surgeon, Dr. D. Y. Patil Vidyapeeth, Pune, Dept. of Oral & Maxillofacial Surgery, Pimpri

2Professor, Dr. D. Y. Patil Vidyapeeth, Pune, Dept. of Oral & Maxillofacial Surgery, Pimpri

3Reader, Dept. of Oral & Maxillofacial Surgery, D. Y. Patil Dental School, Lohegaon, Pune

4PG Trainee, Dr. D. Y. Patil Vidyapeeth, Pune, Dept. of Oral & Maxillofacial Surgery, Pimpri

5Professor, Dr. D. Y. Patil Vidyapeeth, Pune. Dept. of Public Health Dentistry

*Corresponding Author: Dr Pradnya Kakodkar, Professor, Dr D Y Patil Vidyapeeth, Dept. of Public Health Dentistry, Pimpri, Pune, 411018. Phone: +919881409089, Email: pradnya.kakodkar@gmail.com

Online published on 20 March, 2019.

Abstract

Fear of the dentist and dental surgical procedure is a common and potentially distressing problem. Thus, the use of oral anxiolysis is indicated for anxious patients. Aim: -to evaluate and compare efficacy of (oral) diazepam and buspirone in reducing anxiety and discomfort in mandibular third molar surgery.

A prospective, double blinded, comparative spilt mouth, cross-over study was conducted on 28 patients requiring surgical extraction of bilaterally impacted mandibular third molar. Patient were categorized into two groups: Group A were prescribed tablet diazepam 5mg and Group B were prescribed tablet buspirone 10mg respectively. After a wash out period of 3 weeks the groups were crossed over and the sequence of tablets was reversed. Anxiety levels were recorded on Gatchel's anxiety scale before surgery, 30 minutes after medication, intraoperative, post operatively. Comfort level was subjectively assessed.

The results showed that there was no significant difference in the anxiety level in the diazepam group but there was a significant reduction in anxiety in the buspirone tablet group from pre-operative to postoperatively. The subjective comparison of comfort level showed that 78% participants were more comfortable using tablet buspirone, while, only 44% were comfortable with tablet diazepam.

This study reveals that buspirone is comparatively more effective than diazepam to reduce anxiety. Also, the patients are more comfortable with buspirone postoperatively.

Keywords

Fear, Anxiety, Diazepam, Buspirone, Anxiety Scale, Comfort