Indian Journal of Public Health Research & Development

Multidrug Resistance Tuberculosis (MDR-TB) an emerging and a growing threat to tuberculosis control program all over the world. This problem is of special concern because second-line drugs required for its treatment are often unavailable, are far more expensive than the first-line drugs, with only 65–75% efficacy, and have side effects that may require hospitalization. The reasons quoted for the same was inconsistent and or interrupted drug intake or supply.

To study programme related variables present in Multidrug Resistance Tuberculosis cases.

This case-control study was carried out for the assessment of programme related influencing factors for Multidrug Resistance Tuberculosis among TB patients enrolled for DOTS under RNTCP during the period of 2016 to 2018 at various sub-district levels.

Majority of MDR cases (96.2%) were visited by senior tuberculosis supervisor, and 98.1% by DOTS providers. Among treatment profile 98.1% MDR patient were on categories II in which relapse (57.8%), treatment failure (33.3%) and default were 8.8%. High proportion of sputum samples were sent to Designated Microscopy centre (51.9%) at grass root level followed by Districts Tuberculosis center (18.3%) and at Tuberculosis unit (16.3%). Most patients (78.8% cases) lived at a distance less than 2.5 kilometer from DOTS provider.

If the guideline given by the Revised National Tuberculosis Control programme is implemented smoothly at the level of District then there would not be any program based reason to develop resistance to primary anti tubercular drugs.