1Research Scholar, Professor, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research (BIHER), Chennai, Tamil Nadu, India
2Professor and Head of Department Department of Microbiology, Research Lab for Oral and Systemic Health, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research (BIHER), Chennai, Tamil Nadu, India
3Reader, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research (BIHER), Chennai, Tamil Nadu, India
4Post Graduate Student, Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research (BIHER), Chennai, Tamil Nadu, India
*Corresponding Author: S. Leena Sankari, Professor, Department of Oral pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India Phone: +919840591791, Email: drleena.sankari@gmail.com
Online published on 4 June, 2019.
There is increasing evidence of immune diseases in the last few decades. Immune reaction doesn't occur against our own tissue antigens. This is as a result of “Tolerance to self-antigens” which is acquired by varied mechanisms. Failure in immune recognition of self and injury to self-tissues (autoimmunity) results from a loss of self-tolerance. This article will discuss the mechanisms of self-tolerance and the break down mechanism in autoimmunity.
Autoimmune, antigen, self tolerance, rejection, immune recognition
