1Department of General Surgery, Almahaweel General Hospital, Iraq
2Collage of Medicine, AL-Nahrain University, Iraq
3Clinical Pharmacist, Baghdad Medical City, Iraq
To investigate the efficiency of single dose of (dexamethasone 4mg) intravenously in reduction of postoperative nausea and vomiting, and compared it to metoclopramide.
A prospective placebo controlled study involved total of (150) patients diagnosed clinically and radiologically as cholecystitis and admitted for elective laparoscopic cholecystectomy. Patients were randomly divided into three groups, each with 50 patients, the incidence of nausea and/or vomiting was recorded in three groups with in first 6 hours postoperative and then during the next eighteen hours of the first postoperative day.
Nausea and vomiting significantly reduced in the group receiving dexamethasone on the day of operation
Dexamethasone (4mg) as single prophylactic dose is effective in the prevention of postoperative nausea and vomiting in laparoscopic cholecystectomy. Additionally dexamethasone is more effective than metoclopramide in reducing postoperative nausea and vomiting following laparoscopic cholecystectomy.
Dexamethasone, postoperative, nausea, vomiting, prevention
