1Research Scholar, Bharath Institute of Higher Education and Research, Selaiyur, Chennai
2Professor and Head, Department of Biochemistry, Sree Balaji Dental College, Bharath University, Pallikaranai, Chennai
3Junior Consultant, Apollo Hospital, Chennai
Online published on 4 June, 2019.
Insulin resistance is communal in patients with PCOS-Polycystic Ovary Syndrome. Serum copper, zinc, magnesium are measured and it is correlatedwith insulin resistance.
The present study intended to determine correlations among insulin Resistance and minerals like copper, zinc, magnesium inpatients with PCOS.
The subjects were identified from gynecology OPD of private medical college in Tamilnadu. The study involved 200 femaleof age 15–45 years (100female had PCOS and the other 100 female werecontrols).
HOMA wasmeaningfully higher in female with PCOS in contrast with Control. There was a significant correlation of copper, zinc and magnesium with insulin resistance. It was observed that the levels of copper and zinc increases with patient showing insulin resistance while magnesium was lowered in the same.
There is a significant correlation between the levels of copper, zinc, magnesium and IR in patients with PCOS.
Copper, zinc, magnesium, HOMAIR, PCOS
